Intravenous vitamin C in adults with sepsis in the intensive care unit | NEJM

Departments of medicine (F. Lamontagne, M.-CB, HQM) and anesthesiology (FD), the University of Sherbrooke, the Department of Pharmacy (BB), the Research Center of the CHU de Sherbrooke, the Center Integrated University of Health and Social Services of Estrie–Centre Hospitalier Universitaire de Sherbrooke (F. Lamontagne, M.-HM, JM, FD, E. Carbonneau) and Bishop’s University (DC), Sherbrooke, QC, the Division of Orthopedic Surgery, Department of Surgery (SS), Department of Medicine (DJC, GHG, BR, TM, MOM, EPB-C., SSK), Department of Methods, Evidence and Impact of Health Research (DJC, GHG , BR, MOM, LH, EPB-C., FC), and Population Health Research Institute (EPB-C.), McMaster University, Department of Critical Care, St. Joseph’s Healthcare Hamilton (DJC), Intensive Care Unit, Juravinski Hospital (TM), and Respiratory Therapy, Hamilton Health Sciences (LH), Hamilton, ON, the Department of Critical Care Medicine, Sunnybrook Health Sciences Center (R. Pin to, NM, NKJA), ta Interdepartmental Division of Critical Care Medicine, University of Toronto (SM, NKJA) and Sinai Health System (SM), Toronto, Departments of Critical Care Medicine (DKH, DMM, MH), Public Health Sciences (AGD) and Medicine (DMM), Queen’s University and Kingston Health Sciences Center (AGD, DMM), Kingston, ON, Department of Pharmacy, Ottawa Hospital (SK), Institute Ottawa Hospital Research Center (SK, IW, R. Porteous) and Department of Surgery, University of Ottawa (AJES), Ottawa, ON, Massawippi Valley Foundation, Ayer’s Cliff, QC (DC) , the Department of Medicine, University of Montreal (MC), the Center Hospitalier de l’Université de Montréal (MC , ML, E. Charbonney), the Research Center of the Hôpital du Sacré-Coeur de Montréal (E. Charbonney), and Departments of Medicine and Critical Care, McGill University Health Center (JS), Montreal, QC, Department of Medicine (F. Lauzier) and Division of Critical Care Medicine, Department of Anesthesiology and Intensive Care (F. Lauzier, AFT), Laval University, Intensive Care Medicine Department (F. Lauzier, AFT) and Research Center (F. Lauzier, AFT), CHU de Québec–Laval University, Québec, QC, Department of Critical Care Medicine, University of Alberta, Edmonton (OGR, DJK), the Division of Intensive Care, Department of Medicine, CHU Dr Georges L. Dumont, Moncton, NB (RL), the Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON (TSM), the Division of Intensive Care Medicine, Island Health Authority, Victoria, BC (GW) and the Department of Medicine, Halton Healthcare, Oakville, ON (SSK) — all in Canada; Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital (R. Parke, SPM), and School of Nursing, University of Auckland (R. Parke), Auckland, New York Institute of Medical Research Zealand, Newtown (R. Parke, SPM, PJY), Intensive Care Unit, Wellington Hospital, Wellington (PJY) and Department of Surgical Sciences, University of Otago, Dunedin (PT) – all in New Zealand Zeeland; the Department of Critical Care Medicine, Apollo Hospitals, Chennai and George Institute for Global Health, New Delhi – both in India (BKTV); the Intensive Medicine Department, Raymond-Poincaré Hospital (Assistance Publique–Hospitals of Paris [AP-HP]), and SEPSIS University Hospital Federation, Garches (DA), National Institute of Health and Medical Research, Paris-Saclay University Campus UVSQ, Versailles (DA), and Intensive Medicine Resuscitation Department, AP-HP, University Hospitals Henri-Mondor, CARMAS Clinical Research Group and Mondor Biomedical Research Institute, Paris Est Créteil University, Créteil (AM-D.) — all in France; the College of Medicine, King Saud Bin Abdulaziz University of Health Sciences, King Abdullah International Center for Medical Research and Department of Critical Care, King Abdulaziz Medical City, Ministry of Health Affairs National Guard – all at Riyadh, Saudi Arabia (YMA); and Australian and New Zealand Center for Critical Care Research, Monash University, Melbourne, VIC, Australia (R. Parke, SPM, PJY).

Dr. Lamontagne can be contacted at [email protected] or at the Department of Medicine, Université de Sherbrooke, 3001 12th Ave. N., Sherbrooke, Quebec J1H 5N4, Canada. Dr. Adhikari can be contacted at [email protected] or at the Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Ave., Room D1.08, Toronto M4N 3M5, Canada.

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